Alaska Airlines flight AS 4780: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 13:15 Chicago O'Hare (ORD) 3 16:48 Jacksonville (JAX)
AS 4780 Non-stop Airbus A319 (319) 2:33 Effective 2025-09-03 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 3208)
Daily 13:35 Milwaukee (MKE) 14:40 Chicago O'Hare (ORD) 3
AS 4780 Non-stop Canadair CRJ 700 (CR7) 1:05 Effective 2025-08-06 through 2025-09-02
Codeshare flight, operated by American Airlines.(AA 6360)
Daily 16:50 Chicago O'Hare (ORD) 3 20:28 Orlando (MCO) B
AS 4780 Non-stop Airbus A321 (321) 2:38 Effective 2025-06-05 through 2025-07-04
Codeshare flight, operated by American Airlines.(AA 486)
Daily 16:53 Chicago O'Hare (ORD) 3 20:40 Orlando (MCO) B
AS 4780 Non-stop Airbus A321 (321) 2:47 Effective 2025-07-05 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 486)
Daily 18:30 Chicago O'Hare (ORD) 3 21:30 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:00 Effective 2025-10-06 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 18:30 Chicago O'Hare (ORD) 3 21:18 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:48 Effective 2025-11-02 through 2025-12-02
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 18:30 Chicago O'Hare (ORD) 3 21:21 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:51 Effective 2025-12-03 through 2025-12-17
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 18:30 Chicago O'Hare (ORD) 3 21:23 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:53 Effective from 2026-02-12
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 19:00 Chicago O'Hare (ORD) 3 21:47 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:47 Valid until 2025-05-04
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 19:09 Chicago O'Hare (ORD) 3 22:00 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:51 Effective 2025-05-05 through 2025-05-22
Codeshare flight, operated by American Airlines.(AA 3765)
Fri 19:09 Chicago O'Hare (ORD) 3 22:00 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 175 (E75) 1:51 Operates only on 2025-05-23
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 19:09 Chicago O'Hare (ORD) 3 22:00 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:51 Effective 2025-05-24 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 20:20 Chicago O'Hare (ORD) 3 23:21 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:01 Effective 2025-12-18 through 2026-01-05
Codeshare flight, operated by American Airlines.(AA 3765)
Daily 20:20 Chicago O'Hare (ORD) 3 23:17 Rochester (ROC)
AS 4780 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 3765)
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This flight number is listed as serving the following routes:
Alaska Airlines flight AS 4780: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:

Alaska Airlines AS4780
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3208)
Duration: 2:33, non-stop
Airbus A319 (319)

Alaska Airlines AS4780
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6360)
Duration: 1:05, non-stop
Canadair CRJ 700 (CR7)

Alaska Airlines AS4780
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 486)
Duration: 2:38, non-stop
Airbus A321 (321)

Alaska Airlines AS4780
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 486)
Duration: 2:47, non-stop
Airbus A321 (321)

Alaska Airlines AS4780
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 2:00, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:48, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:51, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:53, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:47, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective 2025-05-05 through 2025-05-22
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:51, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Operates only on 2025-05-23
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:51, non-stop
Embraer EMB 175 (E75)

Alaska Airlines AS4780
Effective 2025-05-24 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:51, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 2:01, non-stop
Embraer EMB 170 / EMB 175 (E70)

Alaska Airlines AS4780
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3765)
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Jacksonville (JAX)
  • Chicago O'Hare (ORD) - Orlando (MCO)
  • Chicago O'Hare (ORD) - Rochester (ROC)
  • Milwaukee (MKE) - Chicago O'Hare (ORD)