Alaska Airlines flight AS 4280: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Wed-Sun 06:00 Harrisburg (MDT) 07:12 Chicago O'Hare (ORD) 3
AS 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:12 Effective 2025-10-01 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 3351)
Daily 06:57 Fayetteville/Springdale (XNA) 08:22 Dallas Fort Worth (DFW)
AS 4280 Non-stop Embraer EMB 175 (E75) 1:25 Effective 2025-05-05 through 2025-05-14
Codeshare flight, operated by American Airlines.(AA 4005)
Daily 08:00 Nashville (BNA) 10:22 Dallas Fort Worth (DFW)
AS 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:22 Effective from 2026-02-12
Codeshare flight, operated by American Airlines.(AA 4247)
Daily 08:24 Dallas Fort Worth (DFW) 12:15 Charlotte (CLT)
AS 4280 Non-stop Airbus A321 (321) 2:51 Effective 2025-08-06 through 2025-09-02
Codeshare flight, operated by American Airlines.(AA 1690)
Mon,Wed,Sat,Sun 08:47 Philadelphia (PHL) F 10:44 Asheville/Hendersonville (AVL)
AS 4280 Non-stop Embraer ERJ 145 (ER4) 1:57 Effective 2025-05-31 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 5962)
Daily 09:45 Chicago O'Hare (ORD) 3 12:10 New Orleans (MSY)
AS 4280 Non-stop Boeing 737-800 (738) 2:25 Effective 2025-10-06 through 2025-10-25
Codeshare flight, operated by American Airlines.(AA 1195)
Daily 11:39 Nashville (BNA) 14:00 Dallas Fort Worth (DFW)
AS 4280 Non-stop Boeing 737-800 (738) 2:21 Effective 2025-11-21 through 2025-12-02
Codeshare flight, operated by American Airlines.(AA 2648)
Daily 13:28 New Orleans (MSY) 16:05 Chicago O'Hare (ORD) 3
AS 4280 Non-stop Boeing 737-800 (738) 2:37 Effective 2025-10-06 through 2025-10-25
Codeshare flight, operated by American Airlines.(AA 1195)
Mon-Fri,Sun 14:27 Amarillo (AMA) 15:45 Dallas Fort Worth (DFW) E
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:18 Effective 2025-09-14 through 2025-09-26
Codeshare flight, operated by American Airlines.(AA 4913)
Mon-Fri,Sun 15:03 Madison (MSN) 16:08 Chicago O'Hare (ORD) 3
AS 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:05 Effective 2025-09-07 through 2025-09-12
Codeshare flight, operated by American Airlines.(AA 3675)
Mon,Tue,Sun 15:03 Madison (MSN) 16:08 Chicago O'Hare (ORD) 3
AS 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:05 Effective 2025-09-28 through 2025-09-30
Codeshare flight, operated by American Airlines.(AA 3675)
Sat 15:43 Dallas Fort Worth (DFW) E 17:07 Amarillo (AMA)
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:24 Effective 2025-05-17 through 2025-05-24
Codeshare flight, operated by American Airlines.(AA 6365)
Tue 16:20 Reno (RNO) 18:10 Phoenix Sky Harbor (PHX) 4
AS 4280 Non-stop Embraer EMB 175 (E75) 1:50 Operates only on 2025-06-03
Codeshare flight, operated by American Airlines.(AA 3691)
Mon,Tue 16:23 Dallas Fort Worth (DFW) 17:42 Wichita (ICT)
AS 4280 Non-stop Embraer EMB 175 (E75) 1:19 Effective 2025-07-07 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 3691)
Daily 16:48 Dallas Fort Worth (DFW) 20:16 Charlotte (CLT)
AS 4280 Non-stop Airbus A321 (321) 2:28 Effective 2025-12-03 through 2025-12-17
Codeshare flight, operated by American Airlines.(AA 522)
Daily 17:07 Dallas Fort Worth (DFW) 20:36 Charlotte (CLT)
AS 4280 Non-stop Airbus A321 (321) 2:29 Effective 2025-12-18 through 2026-01-05
Codeshare flight, operated by American Airlines.(AA 522)
Sat 17:38 Amarillo (AMA) 18:55 Dallas Fort Worth (DFW) E
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:17 Effective 2025-05-17 through 2025-05-24
Codeshare flight, operated by American Airlines.(AA 6365)
Mon,Thu,Fri,Sun 18:58 Nashville (BNA) 21:05 Dallas Fort Worth (DFW)
AS 4280 Non-stop Boeing 737-800 (738) 2:07 Effective 2025-06-08 through 2025-07-03
Codeshare flight, operated by American Airlines.(AA 1769)
Tue-Sat 19:05 Chicago O'Hare (ORD) 3 21:37 New Orleans (MSY)
AS 4280 Non-stop Embraer EMB 175 (E75) 2:32 Effective 2025-06-05 through 2025-06-11
Codeshare flight, operated by American Airlines.(AA 4432)
Tue,Wed,Sat 19:05 Chicago O'Hare (ORD) 3 21:37 New Orleans (MSY)
AS 4280 Non-stop Embraer EMB 175 (E75) 2:32 Effective 2025-06-14 through 2025-07-02
Codeshare flight, operated by American Airlines.(AA 4432)
Daily 19:09 Dallas Fort Worth (DFW) 22:40 Charlotte (CLT)
AS 4280 Non-stop Airbus A321 (321) 2:31 Effective 2025-11-02 through 2025-11-20
Codeshare flight, operated by American Airlines.(AA 522)
Mon-Fri,Sun 19:10 Philadelphia (PHL) F 20:59 Cleveland Hopkins (CLE)
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:49 Effective 2025-05-15 through 2025-05-30
Codeshare flight, operated by American Airlines.(AA 5279)
Daily 19:30 Dallas Fort Worth (DFW) 23:11 Charlotte (CLT)
AS 4280 Non-stop Airbus A321 (321) 2:41 Effective 2025-10-26 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 522)
Daily 19:50 Phoenix Sky Harbor (PHX) 4 20:08 San Diego (SAN) 2
AS 4280 Non-stop Airbus A321 (321) 1:18 Effective 2026-01-07 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 1195)
Wed-Sun 20:23 Phoenix Sky Harbor (PHX) 4 22:57 Spokane (GEG)
AS 4280 Non-stop Airbus A319 (319) 2:34 Effective 2025-07-05 through 2025-08-03
Codeshare flight, operated by American Airlines.(AA 339)
Daily 20:24 Phoenix Sky Harbor (PHX) 4 22:59 Spokane (GEG)
AS 4280 Non-stop Airbus A320 (320) 2:35 Valid until 2025-05-04
Codeshare flight, operated by American Airlines.(AA 339)
Wed-Sat 20:34 Oklahoma City (OKC) 21:40 Dallas Fort Worth (DFW) E
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:06 Effective 2025-09-03 through 2025-09-06
Codeshare flight, operated by American Airlines.(AA 4893)
Sat 20:34 Oklahoma City (OKC) 21:40 Dallas Fort Worth (DFW) E
AS 4280 Non-stop Canadair CRJ 700 (CR7) 1:06 Effective 2025-09-13 through 2025-09-27
Codeshare flight, operated by American Airlines.(AA 4893)
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This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 4280: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4280
06:00
Harrisburg (MDT)

07:12
Chicago O'Hare (ORD) 3
Effective 2025-10-01 through 2025-10-05
Mon
-
Tue
-
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3351)
Duration: 2:12, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4280
06:57
Fayetteville/Springdale (XNA)

08:22
Dallas Fort Worth (DFW)
Effective 2025-05-05 through 2025-05-14
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4005)
Duration: 1:25, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4280
08:00
Nashville (BNA)

10:22
Dallas Fort Worth (DFW)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4247)
Duration: 2:22, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4280
08:24
Dallas Fort Worth (DFW)

12:15
Charlotte (CLT)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1690)
Duration: 2:51, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
08:47
Philadelphia (PHL) F

10:44
Asheville/Hendersonville (AVL)
Effective 2025-05-31 through 2025-06-04
Mon
Tue
-
Wed
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5962)
Duration: 1:57, non-stop
Embraer ERJ 145 (ER4)
Alaska Airlines AS4280
09:45
Chicago O'Hare (ORD) 3

12:10
New Orleans (MSY)
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1195)
Duration: 2:25, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4280
11:39
Nashville (BNA)

14:00
Dallas Fort Worth (DFW)
Effective 2025-11-21 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 2648)
Duration: 2:21, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4280
13:28
New Orleans (MSY)

16:05
Chicago O'Hare (ORD) 3
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1195)
Duration: 2:37, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4280
14:27
Amarillo (AMA)

15:45
Dallas Fort Worth (DFW) E
Effective 2025-09-14 through 2025-09-26
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4913)
Duration: 1:18, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4280
15:03
Madison (MSN)

16:08
Chicago O'Hare (ORD) 3
Effective 2025-09-07 through 2025-09-12
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3675)
Duration: 1:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4280
15:03
Madison (MSN)

16:08
Chicago O'Hare (ORD) 3
Effective 2025-09-28 through 2025-09-30
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3675)
Duration: 1:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4280
15:43
Dallas Fort Worth (DFW) E

17:07
Amarillo (AMA)
Effective 2025-05-17 through 2025-05-24
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 6365)
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4280
16:20
Reno (RNO)

18:10
Phoenix Sky Harbor (PHX) 4
Operates only on 2025-06-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 3691)
Duration: 1:50, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4280
16:23
Dallas Fort Worth (DFW)

17:42
Wichita (ICT)
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 3691)
Duration: 1:19, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4280
16:48
Dallas Fort Worth (DFW)

20:16
Charlotte (CLT)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 522)
Duration: 2:28, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
17:07
Dallas Fort Worth (DFW)

20:36
Charlotte (CLT)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 522)
Duration: 2:29, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
17:38
Amarillo (AMA)

18:55
Dallas Fort Worth (DFW) E
Effective 2025-05-17 through 2025-05-24
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 6365)
Duration: 1:17, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4280
18:58
Nashville (BNA)

21:05
Dallas Fort Worth (DFW)
Effective 2025-06-08 through 2025-07-03
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 1769)
Duration: 2:07, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4280
19:05
Chicago O'Hare (ORD) 3

21:37
New Orleans (MSY)
Effective 2025-06-05 through 2025-06-11
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 2:32, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4280
19:05
Chicago O'Hare (ORD) 3

21:37
New Orleans (MSY)
Effective 2025-06-14 through 2025-07-02
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 2:32, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4280
19:09
Dallas Fort Worth (DFW)

22:40
Charlotte (CLT)
Effective 2025-11-02 through 2025-11-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 522)
Duration: 2:31, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
19:10
Philadelphia (PHL) F

20:59
Cleveland Hopkins (CLE)
Effective 2025-05-15 through 2025-05-30
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 5279)
Duration: 1:49, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4280
19:30
Dallas Fort Worth (DFW)

23:11
Charlotte (CLT)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 522)
Duration: 2:41, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
19:50
Phoenix Sky Harbor (PHX) 4

20:08
San Diego (SAN) 2
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1195)
Duration: 1:18, non-stop
Airbus A321 (321)
Alaska Airlines AS4280
20:23
Phoenix Sky Harbor (PHX) 4

22:57
Spokane (GEG)
Effective 2025-07-05 through 2025-08-03
Mon
-
Tue
-
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 339)
Duration: 2:34, non-stop
Airbus A319 (319)
Alaska Airlines AS4280
20:24
Phoenix Sky Harbor (PHX) 4

22:59
Spokane (GEG)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 339)
Duration: 2:35, non-stop
Airbus A320 (320)
Alaska Airlines AS4280
20:34
Oklahoma City (OKC)

21:40
Dallas Fort Worth (DFW) E
Effective 2025-09-03 through 2025-09-06
Mon
-
Tue
-
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 4893)
Duration: 1:06, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4280
20:34
Oklahoma City (OKC)

21:40
Dallas Fort Worth (DFW) E
Effective 2025-09-13 through 2025-09-27
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 4893)
Duration: 1:06, non-stop
Canadair CRJ 700 (CR7)
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This flight number is listed as serving the following routes:
  • Amarillo (AMA) - Dallas Fort Worth (DFW)
  • Chicago O'Hare (ORD) - New Orleans (MSY)
  • Dallas Fort Worth (DFW) - Charlotte (CLT)
  • Dallas Fort Worth (DFW) - Wichita (ICT)
  • Fayetteville/Springdale (XNA) - Dallas Fort Worth (DFW)
  • Harrisburg (MDT) - Chicago O'Hare (ORD)
  • Madison (MSN) - Chicago O'Hare (ORD)
  • Nashville (BNA) - Dallas Fort Worth (DFW)
  • Oklahoma City (OKC) - Dallas Fort Worth (DFW)
  • Philadelphia (PHL) - Asheville/Hendersonville (AVL)
  • Philadelphia (PHL) - Cleveland Hopkins (CLE)
  • Phoenix Sky Harbor (PHX) - San Diego (SAN)
  • Phoenix Sky Harbor (PHX) - Spokane (GEG)
  • Reno (RNO) - Phoenix Sky Harbor (PHX)
All Alaska Airlines flights
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